TRACK D: Advanced Pharmacoepidemiology (English)
Tracks
Track 4
| Saturday, October 12, 2024 |
| 8:00 - 17:00 |
| Yasuda Auditorium |
Speaker
Instructor Of Medicine And Epidemiology Benjamin Bates
Rutgers
Advanced Course- Methods in Environmental Pharmacoepidemiology
Abstract
The World Health Organization has described climate change as the “single biggest health threat facing humanity.” Factors associated with climate change, such as elevated air pollution levels, more extreme temperatures, and increased frequency and intensity of severe storms, can directly and indirectly impact health. Medications have the potential to exacerbate or mitigate climate-related adverse events and may also be disrupted by extreme climate disasters. Concomitantly, improper disposal or misuse of medications has the potential to impact the environment and subsequently adversely impact our health. While measuring drug exposure can be difficult, understanding how to define and assess environmental exposure has its own complexities. Innovative and unique methodologies are being used to evaluate the interplay between environment and health.
In this Advanced Session on Methods in Environmental Pharmacoepidemiology, we will provide an outline to understand environmental pharmacoepidemiology, including description of broad areas of pharmacoepidemiology, introduction to commonly studied exposures and methodologies to collect and analyze data, and overview of example publications. By the end of the course, the participant should be able to describe environmental pharmacoepidemiology, discuss common types of exposures and methodologic approaches, and begin to formulate how environmental pharmacoepidemiology may be relevant to their own research.
In this Advanced Session on Methods in Environmental Pharmacoepidemiology, we will provide an outline to understand environmental pharmacoepidemiology, including description of broad areas of pharmacoepidemiology, introduction to commonly studied exposures and methodologies to collect and analyze data, and overview of example publications. By the end of the course, the participant should be able to describe environmental pharmacoepidemiology, discuss common types of exposures and methodologic approaches, and begin to formulate how environmental pharmacoepidemiology may be relevant to their own research.
Biography
Benjamin Bates, MD, is an Instructor of Medicine at Rutgers-Robert Wood Johnson Medical School and Core Member of Rutgers Center for Pharmacoepidemiology and Treatment Science. His research focuses on the treatment and health outcomes of patients with cancer. He has received research funding from the New Jersey Commission on Cancer Research and the Robert E. Leet and Clara Guthrie Patterson Trust Mentored Research Award. Most pertinent to the ACPE symposium, “Environmental Pharmacoepidemiology Around the World: Climate Change, Medications, and Health Outcomes,” he is currently leading research investigating the impact of climate events, namely air pollution and severe storms, on cancer treatment utilization, effectiveness, and health outcomes among patients with cancer.
Helga Gardarsdottir
Professor Real world data for decision making on medicines
Utrecht University
Presenter
Biography
Helga Gardarsdottir is professor in use of Real world data for decision making on medicines at the Division of Pharmacoepidemiology & Clinical Pharmacology (Utrecht University, NL). Additionally, she holds the position of adjunct professor of Pharmacoepidemiology at the University of Iceland in Reykjavik.
Her primary research interests include the application and development of innovative approaches to generate and analyse real world data on safety and effectiveness of medicines to inform regulatory and clinical decision making. Her special research interest involve assessing impact of drug regulation on safe and effective use in populations. Prof Gardarsdottir was trained as a pharmacist (SE) and a pharmacoepidemiologist (NL). She has led and participated in several international multi-country research projects including the IMI-PROTECT project, the IMI Trials@home project and several EMA tendered studies on behalf of the EU Pharmacoepidemiology and Pharmacovigilance Research Network. She is the co-chair of the ENCePP steering group, a member of the ENCePP working group responsible for the “Guide on Methodologal Standards in Pharmacoepidemiology“, co-led the Real-World Evidence Task Force of the International Society of Pharmacoepidemiology (2019-2022) and is an associate editor of the journal ‘Pharmacoepidemiology & Drug Safety’
Masao Iwagami
University of Tsukuba
Presenter
Biography
Prof. Masao Iwagami, MD, MPH, MSc, PhD, FISPE is a clinical Epidemiologist, Professor in the Institute of Medicine, University of Tsukuba, Japan, Honorary Assistant Professor in the Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine (LSHTM), UK, and Specialist for pharmacoepidemiology in the Office of Pharmacovigilance II, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan. He graduated from the University of Tokyo in 2008, completed his internship and nephrology residency in Japanese hospitals, received the Educational Commission for Foreign Medical Graduates certificate in the USA in 2010, and worked as a Research Assistant Professor in the Department of Haemodialysis and Apheresis, the University of Tokyo Hospital in 2013. He studied clinical epidemiology at the School of Public Health, the University of Tokyo in 2012, at MSc Epidemiology in 2013/2014 and PhD Epidemiology and Population Health in 2014-2018 at LSHTM.
He is the Associate Editor of Pharmacoepidemiology and Drug Safety, and the Chair in the International Affairs Committee of Japanese Society of Pharmacoepidemiology.
Takuya Kawahara
Clinical Research Promotion Center, The University of Tokyo Hospital
Presenter
Biography
Takuya Kawahara is a research associate serving as a clinical biostatistician at the Clinical Research Promotion Center, The University of Tokyo Hospital. After obtaining a Ph.D. in Health Sciences from the University of Tokyo in 2019, he served as a Postdoctoral Research Fellow at the Department of Population Medicine, Harvard Medical School. His primary interest lies in developing and applying causal inference methods for clinical studies to enhance the understanding of treatment effects. This includes handling time-varying treatments, competing events, truncation by death, missing data, principal stratification, and causal survival analysis. His collaborative research spans various fields, including oncology, neurology, pulmonary surgery, palliative care, behavioral studies, and epidemiology.
Mr. Edward Chia-Cheng Lai
Educational Program Director
School Of Pharmacy, Institute Of Clinical Pharmacy And Pharmaceutical Sciences
Presenter
Biography
Associate Professor Edward Chia-Cheng Lai specializes in pharmacoepidemiology, with a focus on research projects using cross-center and cross-national databases. He has received solid training in research methodology. He has published approximately 90 research papers in top-tier journals, including BMJ, Annals of Internal Medicine, and Clinical Pharmacology & Therapeutics. His articles have been cited over 1,000 times. Recognized for his outstanding performance in research methodology, he was invited to become the Associate Editor of the official journal of the International Society for Pharmacoepidemiology (ISPE), Pharmacoepidemiology and Drug Safety, in 2013. He reviews over 30 research papers annually and invites more than 100 domestic and international reviewers to assist in the peer-review process, demonstrating significant academic influence.
Dr Joshua Lin
Harvard Medical School
Presenter
Biography
Dr. Lin is a Pharmacoepidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital and a practicing hospitalist at the Massachusetts General Hospital. He is an Associate Professor at Harvard Medical School and the Executive Director of the Mass General Brigham (MGB) Center for Integrated Healthcare Data Research. He has led an initiative to link the multiple administrative claims data with EHR of the Accessible Research Commons for Health (ARCH), a clinical data research network (CDRN) of the Patient-Centered Clinical Research Network (PCORnet) comprising 11 major medical centers across the U.S. He has led six US national NIH R01 research projects aiming to integrate insurance claims data with EHR data to improve the validity of comparative effectiveness research in vulnerable populations, including people living with dementia and older adults with high frailty or multiple co-morbidities. His long-term career goal is to establish a rigorous and generalizable framework to optimize causal treatment effect estimation based on EHR and claims data to inform personalized prescribing.
Lecturer/Assistant Prof Kenneth Man
University College London
Presenter
Biography
Kenneth Man is a medical statistician and epidemiologist serving as a Lecturer/Assistant Professor in Pharmacoepidemiology at the UCL School of Pharmacy, London. With extensive experience in medication research utilising Real-World Data from large healthcare databases, Kenneth’s research is focused on paediatric, psychiatric and perinatal pharmacoepidemiology including the safety and effectiveness of medication use, prenatal medication exposures, and global psychotropic medication utilisation. He has been recognised with the Kramer-Pollnow Prize in 2023 and has previously chaired the Asia Pharmacoepidemiology Network (AsPEN).
A/Prof Harish C. Phuleria
Indian Institute of Technology Bombay
Presenter
Biography
Dr. Harish C. Phuleria is an associate professor in Environmental Science and Engineering Department at IIT Bombay, Mumbai, India with ~20 years of experience on environmental monitoring, exposure assessment and environmental health. His primary area of research is assessing the short- and long-term exposures to different environmental stressors such as air pollution and road traffic noise. His specific interest lies in characterizing new exposures e.g. to ultrafine particles, to brown and black carbon and to chemical constituents in aerosols of different source origin, in particular to traffic exhaust in urban areas. He holds bachelor’s degree in Chemistry from University of Delhi, master’s degree in Chemistry and in Environmental Science and Engineering from IIT Delhi and IIT Bombay, respectively and a PhD degree in Environmental Engineering from University of Southern California, Los Angeles.
