Oral presentation 1: Drug Discovery Theme
Tracks
Track 1
Monday, December 2, 2024 |
9:00 AM - 10:30 AM |
Eureka Room 1 |
Speaker
Mr Terrance Lam
Phd student
Monash University
HOXC12 co-ordinates b2-adrenoceptor coupling to a cAMP/calcium feedforward loop to drive invasion.
9:00 AM - 9:15 AMBiography
Terrance is a PhD student from Monash University. His research focuses on understanding compartmentalized signaling of the β2-adrenoceptor within the context of triple-negative breast cancer.
Miss Shaqayeg Ramazani
Honours Student
Monash University
Discovery of PDLIM7 and PTPN9 as novel β2-adrenoceptor protein interactors
9:15 AM - 9:30 AMBiography
Shaqayeq Ramazani completed a Bachelor of Pharmaceutical Sciences Degree at Monash University in 2023. She is currently an Honours student in the Drug Discovery Biology Theme at the Monash Institute of Pharmaceutical Sciences, Monash University. She is investigating protein interactors of the β2-adrenoceptor in the Spatial Organisation of Signalling Lab under the supervision of Associate Professor Michelle Halls and Dr Alastair Keen. Shaqayeq is keen on pursuing her PhD.
Ms Lisa Randall
Ph.d. Candidate
University of the Sunshine Coast
Tomentosenol A, isolated from bee propolis, inhibits TGF-β1/SMAD3 signalling in human fibroblasts
9:30 AM - 9:45 AMBiography
Lisa is a third year PhD candidate in the School of Health, Biomedicine discipline. Her PhD studies are centred around pharmacology, examining the cellular mechanisms of a novel, proposed anti-fibrotic compound isolated from the propolis produced by the Australian Stingless bee, Tetragonula carbonaria. This compound is Tomentosenol A. Her studies have enabled her to gain experience in a broad range of biochemical and molecular laboratory techniques, cell culture and animal models. She presents her findings wherever possible, winning the best poster presentation at the 2023 Australian Society for Medical Research, Post-Graduate Student Symposium. She represented the University of the Sunshine Coast and the Centre for Bioinnovation at the 2023 AusBiotech conference and is currently finalising her first research paper for submission for publication. She is a student member of ASCEPT, ASMR and APSA. In 2024 she has been accepted to present papers at the ASCEPT, APFP & APSA Joint Congress and the UniSC Research Conference.
Miss Jiranan Chotitumnavee
Lecturer
Mahidol University
Induction of S-phase arrest and apoptosis in glioblastoma via the HDAC8 PROTAC
9:45 AM - 10:00 AMBiography
Jiranan Chotitumnavee is a lecturer in the Pharmacology Department at the Faculty of Dentistry, Mahidol University, Thailand. She received her Ph.D. in Medical Science from Kyoto Prefectural University of Medicine in 2022, supported by a scholarship from the Japanese government (MEXT). During her doctoral studies, she conducted research at Kyoto Prefectural University of Medicine and Osaka University, where she focused on developing a selective HDAC8 proteolysis-targeting chimera that promotes HDAC8 degradation through the ubiquitin-proteasome system. Her research interests include medicinal chemistry and the chemical biology of epigenetic modulators, particularly their mechanisms of action in cancer.
Miss Jana Zielinski
Phd Candidate
The University of Melbourne
Inhibition of CK1δ Attenuates IL-1α-Induced Epithelial-Mesenchymal Transition in Human Lung Epithelial Cells
10:00 AM - 10:15 AMBiography
Jana graduated from the University of Melbourne in 2020 with a Bachelor of Science majoring in Pharmacology. She received her Honours degree in 2021 under the supervision of Prof. Alastair Stewart, with the thesis titled: “The Art and Artefact of Static Culture”. Jana then began her PhD in 2022 with Prof. Alastair Stewart focusing on the characterisation of Casein Kinase 1 delta in circadian rhythm and cancer tumorigenesis. Her research goals include advancing the use of microphysiological systems for in vitro drug discovery. She was a general committee member of the ASCEPT student forum in 2023.
Mr Vijayraghavan Seshadri
Phd Candidate
University of Tasmania
Exploring and Targeting Calcium Signaling Pathways in Cellular Senescence
10:15 AM - 10:30 AMBiography
I am current final year PhD candidate at the department of pharmacology, university of Tasmania. I am currently doing my research at the department of Pharmacology, Biomedicine discovery institute, Monash university under the supervision of Dr Iman Azimi. My research investigates the role of calcium signalling in cellular ageing. In my current research, I have developed high throughput fluorescence microscopy-based methods for detecting cellular senescence markers. We have also discovered compounds that can be re-purposed to target age related pathologies. I am interested in the field of drug discovery in the field of ageing and age-related diseases.
Chair
Arthur Christopoulos
Monash University
Henry Purbrick
Phd Candidate
The University of Western Australia & Harry Perkins Institute of Medical Research