Tuesday, September 23, 2025

10:30 AM - 12:00 PM

Grand Copthorne Waterfront Hotel - Waterfront Ballroom II

---

Details

Neglected Tropical Diseases (NTDs) affect predominantly marginalized and impoverished communities and receive insufficient funding and research into prevention and treatment. NTDs pose significant public health challenges, affecting over a billion people worldwide. They cause substantial morbidity and mortality, leading to long-term disabilities, economic losses, and hindering of socioeconomic development. Many NTDs have limited effective drugs available, and these are often used at suboptimal doses. This can cause treatment failures and development of drug resistance. Determining the optimal dose in a population requires quantification of the dose –exposure – therapeutic efficacy relationship. This can be achieved through pre-clinical and clinical studies in combination with pharmacokinetic and pharmacodynamic modelling. This symposium provides an overview of the importance, impact and use of pharmacokinetic and pharmacodynamic tools in optimizing treatments of NTDs.