Wednesday, September 24, 2025

10:30 AM - 12:00 PM

Grand Copthorne Waterfront Hotel - Grand Ballroom I

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Details

The aim of this workshop is to provide the audience with interactive discussions around drug-drug interactions (DDI) situations with the antifungal drugs. Questions will be asked to the audience using a poll system and the following topics will be highlighted: difference between DDI potential with different antifungals, particularity of interaction on specific pathways, impact of drug administration modalities on the effect of DDI, concentration-inhibition effect, and effect of genotype on DDI. The principles of DDI identification, pre-emptive drug dosage adjustments and therapeutic drug monitoring role to prevent adverse drug reactions in the context of a DDI situation will be described. The symposium will be set-up in three talks: the first entitled “The Usual Suspects: classic DDI with antifungal drugs (azoles, echinocandines and liposomal amphotericin B) and how to avoid/act on them; the second “Lost in translation: a presentation on some controversial DDI examples” aiming at making the audience aware of these DDI and the last one “Deep impact: the role of inflammation and genetics on antifungal DDI”, where the modulation of DDI by these extrinsic and intrinsic factors will be discussed with the audience.