Magnetic Resonance Spectroscopic Imaging (MRSI) is a valuable tool which grants insight into the chemical composition of human tissue. By positioning voxels across both normal and abnormal tissue, systems can be manipulated to produce spectra representative of metabolites occupying that area. Pathologies, including tumours, radiation necrosis and stroke, display characteristic changes in metabolite concentrations which aid in achieving a non-invasive diagnosis. However, the quality of MRSI is largely operator dependent and education on pulse sequences, positioning and shimming is crucial to producing diagnostic spectra. This presentation will act as a “spectroscopy 101” to clinical radiographers and is suitable as an introduction to MRSI for any new faces.