Keynote presentation 7: Spatiotemporal heterogeneity of in vivo immune systems elucidated by intravital imaging technology
Tracks
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| Thursday, July 16, 2026 |
| 4:45 PM - 5:30 PM |
Overview
The Japanese Pharmacological Society (JPS) Lecture I Prof Masaru Ishii
Details
During the last decade, intravital multiphoton microscopy has launched a new trend in the field of life sciences. By using this advanced imaging technique, we have established a new system for visualizing in situ behavior of a diversity of living cells within intact tissues and organs. Intravital imaging has enabled us to grasp in situ behaviors of local immune response in vivo, especially focusing on bone, lung and liver, leading to the identification of the native systems and their responsible cell types. In this talk, I will present the latest advances in imaging-based life sciences for ‘seeing the unseen phenomenon’, especially focusing on spatiotemporal heterogeneity/variability of immune systems in vivo.
Speaker
Prof Masaru Ishii
The University of Osaka
Spatiotemporal heterogeneity of in vivo immune systems elucidated by intravital imaging technology
Biography
Masaru ISHII, M.D., Ph.D. was graduated from the Osaka University Medical School in 1998 and then worked as a physician specializing in rheumatology and internal medicine. He studied in the National Institutes of Health as a Human Frontier Science Program research fellow (2006-2008), as a laboratory chief in the Immunology Frontier Research Center (2008-2013), and then appointed as a full Professor and Chair of the Department of Immunology and Cell Biology, Graduate School of Medicine, The University of Osaka since 2013. The bulk of his studies have so far elucidated the dynamic behaviors of immune cells, especially focusing on tissue-associated macrophages in various organs such as bone/joint, lung and liver, by using intravital multiphoton imaging that he has originally developed. He is currently serving as a Chair of the Immunopharmacology Committee of IUPHAR as well as a co-opted member of the IUPHAR Executive Committee.