Symposium 2: Pharmacology of the aging urinary bladder: from current to novel treatment targets
Tracks
Track 2
Tuesday, July 14, 2026 |
11:15 AM - 1:15 PM |
Details
The prevalence of urinary bladder dysfunction increases with age and is associated with age-related comorbidities such as type 2 diabetes, thus affecting >70% of people aged 60 years and older. This will increase further at the population level with increasing life expectancy. It affects both sexes but about 80% of patients seeking treatment are women. Bladder dysfunction can occur both as overactive bladder/urgency urinary incontinence and as underactive bladder/urinary retention. Underlying causes include dysfunction of the smooth muscle and/oror innervation. Treatments acting on the detrusor smooth muscle are established, whilst those acting at other targets such as the innervation are in development. Recently, attempts are being made to prevent or reverse bladder aging by pharmaceutically exploiting novel insights into the molecular pathophysiology of bladder aging. This symposium will showcase current understanding of the aging bladder and highlight novel pharmacological strategies to prevent or reverse the effects of aging.
Session chair
Martin Michel
Johannes Gutenberg University
Donna Sellers
Professor In Biomedical Science
Bond University
