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Symposium 6: International Clinical and Translational Pharmacology Research to Inform Deprescribing in Old Age

Tracks
Track 6
Tuesday, July 14, 2026
11:15 AM - 1:15 PM

Details

This symposium, led by the Geriatric Committee of the IUPHAR Clinical and Translational Section, highlights international, interdisciplinary, clinical and translational pharmacology innovations to inform deprescribing in older people. Dr Reeve (EMCR pharmacist, chair ADeN, Australia) will discuss progress in evidence synthesis and deprescribing guidelines. Prof Steinman (geriatrician, chair USDeN, USA) will highlight work by USDeN to build capacity in patient centred deprescribing. Prof Thurmann (clinical pharmacologist, Germany) will discuss innovations in design, conduct and interpretation of deprescribing clinical trials. Dr Hayes (EMCR pharmaco-epidemiologist, chair ISPE Geriatric SIG, USA) will describe findings from an ISPE Geriatric SIG-funded systematic review and consensus paper on methodological guidance for real world evidence to guide deprescribing. Dr Mach (EMCR pharmacologist, ASCEPT, Australia) will outline the role of basic pharmacology and pre-clinical models to understand mechanisms and inform deprescribing.


Speaker

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Prof Michael Steinman
University of California, San Francisco and San Francisco VA Medical Center

Building capacity in patient-centred deprescribing: Insights from the US Deprescribing Research Network

Biography

Dr. Steinman is a Professor of Medicine in the Division of Geriatrics at the University of California, San Francisco and the San Francisco VA Medical Center. A geriatrician-researcher, he cares for older adults in outpatient and inpatient settings and conducts research evaluating how older adults use medications, the problems that arise from medication overuse and misuse, and strategies for improving pharmaceutical care for older adults. He is co-principal investigator of the US Deprescribing Research Network, co-Director of the UCSF Pepper Center for Aging Research, and co-chair of the American Geriatrics Society Beers Criteria of Potentially Inappropriate Medications in Older Adults.

Session chair

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Sarah Hilmer
Kolling Institute, Royal North Shore Hospital, NSLHD and University of Sydney

Emily Reeve
Monash University

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