Symposium 6: International Clinical and Translational Pharmacology Research to Inform Deprescribing in Old Age
Tracks
Track 6
| Tuesday, July 14, 2026 |
| 11:15 AM - 1:15 PM |
Details
This symposium, led by the Geriatric Committee of the IUPHAR Clinical and Translational Section, highlights international, interdisciplinary, clinical and translational pharmacology innovations to inform deprescribing in older people.
Dr Reeve (EMCR pharmacist, chair ADeN, Australia) will discuss progress in evidence synthesis and deprescribing guidelines. Prof Steinman (geriatrician, chair USDeN, USA) will highlight work by USDeN to build capacity in patient centred deprescribing. Prof Thurmann (clinical pharmacologist, Germany) will discuss innovations in design, conduct and interpretation of deprescribing clinical trials. Dr Hayes (EMCR pharmaco-epidemiologist, chair ISPE Geriatric SIG, USA) will describe findings from an ISPE Geriatric SIG-funded systematic review and consensus paper on methodological guidance for real world evidence to guide deprescribing. Dr Mach (EMCR pharmacologist, ASCEPT, Australia) will outline the role of basic pharmacology and pre-clinical models to understand mechanisms and inform deprescribing.
Speaker
Prof Michael Steinman
University of California, San Francisco and San Francisco VA Medical Center
Building capacity in patient-centred deprescribing: Insights from the US Deprescribing Research Network
Biography
Dr. Steinman is a Professor of Medicine in the Division of Geriatrics at the University of California, San Francisco and the San Francisco VA Medical Center. A geriatrician-researcher, he cares for older adults in outpatient and inpatient settings and conducts research evaluating how older adults use medications, the problems that arise from medication overuse and misuse, and strategies for improving pharmaceutical care for older adults. He is co-principal investigator of the US Deprescribing Research Network, co-Director of the UCSF Pepper Center for Aging Research, and co-chair of the American Geriatrics Society Beers Criteria of Potentially Inappropriate Medications in Older Adults.
PharmD, PhD Kaley Hayes
Assistant Professor
Brown University
REporting and Methodological Recommendations for Observational Studies Estimating the effects of Deprescribing medications: the International Society for Pharmacoepidemiology-endorsed REMROSE-D Guidance
Biography
Dr. Kaley Hayes is a pharmacoepidemiologist whose research mission is to apply rigorous pharmacoepidemiologic methods to understand how to use medications and vaccines to improve the health of older adults. She earned her PharmD at the University of Pittsburgh and her PhD in Epidemiology at the University of Toronto. Dr. Hayes conducts research using advanced pharmacoepidemiologic designs and causal inference methods to study outcomes among older patients with multiple chronic conditions to understand the benefits and potential harms of medications and vaccines in this vulnerable population.
Session chair
Sarah Hilmer
Kolling Institute, Royal North Shore Hospital, NSLHD and University of Sydney
Emily Reeve
Monash University
