Tuesday, July 14, 2026

11:15 AM - 1:15 PM

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Details

A canonical view of signal transduction has been that cell surface receptors (e.g. GPCRs, receptor tyrosine kinases) live at the membrane to transmit extracellular signals into the cell, before being internalised and switched off. This doesn’t account for the growing number of studies that have identified receptors, or indeed the entire signalling machinery, of so-called cell surface proteins in distinct cellular organelles beyond those required for internalisation. In this symposium, our expert internationally-recognised speakers will highlight recent technological breakthroughs that have allowed us to understand what really lies within these organelles. The therapeutic potential of targeting these receptor locations will be discussed. Confirmed speakers: A/Prof Benjamin Myers: Unconventional GPCR-kinase signaling in primary cilia Dr Vaishnavi Ananthanarayanan: Cargo-motor adaptor proteins at the crossroads of EGFR signalling A/Prof Michelle Halls: Shining a light on GPCR signalling from organelles Two EMCR short talks will be selected from submitted abstracts.

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Session chair