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Oral Presentations 53: Drug Discovery/NAMS 2

Tracks
Track 5
Friday, July 17, 2026
9:00 AM - 10:30 AM

Speaker

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Dr Paris Papagianis
Monash University

Improving silicosis screening using chemical biomarkers in exhaled breath

9:00 AM - 9:15 AM

Abstract

Biography

Dr Paris Papagianis is a Postdoctoral Research Fellow in the Respiratory Pharmacology Lab within the Biomedicine Discovery Institute (BDI) at Monash University. Paris’ core research focus is on lung damage and disease after environmental (bushfire) or occupational (silica dust) exposures. Paris continues to draw links between lung injury and inflammation induced by chemicals in bushfire smoke or by occupational silica dust, both leading to lung fibrosis and silicosis. She was part of the first clinical studies investigating silicosis from engineered stone, which led to the world-first banning of engineered stone in Australia. Now, her team is developing portable screening tools to help identify high-risk workers in remote at-risk occupations such as mining. Paris’s ultimate research goals include providing tools to assist in prevention and earlier detection of silicosis, to better understand how climate change is impacting lung health and to educate consumers and workers about the dangers of inhaled smoke and dust.
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Dr Tracy Josephs
Monash Institute Of Pharmaceutical Sciences

Dynamic Modulation of Amylin Receptor Subtypes by RAMPs Revealed through HDX-MS

9:15 AM - 9:30 AM

Abstract

Biography

Tracy Josephs is a NHMRC Investigator fellow and group leader at the Monash Institute of Pharmaceutical Sciences (MIPS), where she leads the Structural DynOmics of Membrane Proteins Laboratory within the Drug Discovery Biology theme. She completed her PhD in Biochemistry at the University of Otago (New Zealand) and has since built an interdisciplinary research program focused on understanding protein structure and dynamics in physiologically relevant environments. Her work integrates membrane protein function, pharmacogenomics, and disease-relevant signalling mechanisms. Tracy is passionate about translating dynamic structural insights into precision and patient-informed drug discovery.
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Prof Jianfei Long
Fudan University affinitied Huashan hospital

Patient-derived vestibular schwannoma organoids uncover non-surgical therapeutic vulnerabilities via drug screening

9:30 AM - 9:45 AM

Abstract

Biography

Prof. Jianfei Long is an Associate Researcher and MD in Clinical Pharmacy at Fudan University, serving as a Master’s supervisor. She is a clinical pharmacist at Huashan Hospital and a committee member of the Chinese Geriatrics Society. Prof. Long leads multiple projects funded by National Natural Science Foundation of China, has published over ten first-author SCI papers (Impact Factor up to 26.8), and received awards including the Chinese Pharmaceutical Association Outstanding Case Award. His research focuses on gut microbiota in chronic disease and vestibular schwannoma organoid models for drug screening and mechanistic studies.
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Prof Weiying Zhou
Chongqing Medical University

SGK3 promotes ER+ breast cancer by MARCH5-mediated BNIP3 ubiquitination

9:45 AM - 10:00 AM

Abstract

Biography

Weiying Zhou, Ph.D., is a full professor and director of Department of Phamacology at College of Pharmacy in Chongqing Medical University (CQMU). She is a vice chairman of the Chemotherapy Pharmacology Professional Committee of the Chinese Pharmacological Society. Her research interests focus on pharmacology of anti-cancer drugs and anti-metabolic disorder drugs. Her research is also on the basic biological aspects of breast cancer and prostate cancer, such as the mechanisms of invasion and metastasis and chemotherapy resistance. She has published over 30 peer-reviewed articles as the first/corresponding author in the scientific journals including Cancer Cell, British Journal of Pharmacology, Phytomedicine, Journal of Translational Medicine, Neoplasia, npj Breast Cancer, Biochemical Pharmacology, EUR J PHARMACO, and Journal of Drug Targeting.
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Dr Lauren Phillips
University Of Oxford

A novel immunofluorescence assay to determine eNOS phosphorylation within intact resistance arteries

10:00 AM - 10:15 AM

Abstract

Biography

Dr Lauren Phillips studied in biological sciences where she became fascinated with the world of genetics and how changes to our DNA can affect our body’s form and function. She gained diverse research experience whilst investigating novel genetic causes of limb girdle muscular dystrophy using whole exome and whole genome sequencing, before securing a PhD studentship to identify novel genetic causes of Congenital Heart Disease and Cardiomyopathies. Following the completion of her PhD, she joined the Department of Pharmacology at the University of Oxford as a British Heart Foundation funded postdoctoral researcher investigating the mechanism of myoendothelial feedback within the microvasculature. Lauren currently holds a Fellowship by Examination at Magdalen College, Oxford investigating mechanisms of vasoconstriction and relaxation to identify potential therapeutic targets for diseases including hypertension, coronary heart disease and heart failure.
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Prof Haiyang Yu
Tianjin University Of Traditional Chinese Medicine

Siglec-10 modulate the formation of colorectal cancer pre-metastatic niche through immune remodeling

10:15 AM - 10:30 AM

Abstract

Biography

Yu Hai, male, 42, is a professor at Tianjin University of Traditional Chinese Medicine (TCM) and serves as Associate Dean of the Institute of Interdisciplinary Sciences and Deputy Director of the Tianjin Key Laboratory of TCM Pharmacology. His research focuses on TCM pharmacology, particularly in exploring anti-tumor mechanisms of herbal medicines and natural products. He has revealed the regulatory role of the LIF signaling pathway in tumor development, opening new avenues for anti-tumor drug discovery. A recipient of the National “Ten Thousand Talents Program” Young Top-notch Talent award, he has published over 50 SCI papers in journals such as Nature Communications. He also holds editorial roles in several academic journals and committees.

Session chair

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Paris Papagianis
Monash University

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