I am an A/Prof at Monash University and co-leader of the Analytical and Structural Neuropharmacology group in the Drug Discovery Biology Theme at Monash Institute of Pharmaceutical Sciences. My research has been instrumental in the development, dissemination, and uptake of three major paradigms of GPCR drug action: 1) allosteric modulation, which led to my receipt of the 2015 Thomson Reuters Australia Citation & Innovation Award, Pharmacology and Toxicology. 2) biased signalling, which led me to secure a collaborative work with US-based biotech Karuna Therapeutics. 3) bitopic ligands, which led to my receipt of the 2012 BPS/ASCEPT Outstanding New Investigator Award, and 2012 ASCEPT Denis Wade Johnson & Johnson New Investigator Award, and the implementation of the concept in the most prestigious textbooks, the Goodman & Gilman's: The Pharmacological Basis of Therapeutics. In the last 10 years, I have had a sustained record of research income, totalling $6.5M (>75% as CIA).

Dr. Arsalan Yousuf is a Lecturer in Sydney Pharmacy School, The University of Sydney. His research area of interest revolves around targeting membrane GPCR's involved in regulating pain and addiction like Opioid receptors, GABA-B receptors and their interaction with ion channels. His expertise focusses on patch clamp electrophysiology, slice electrophysiology, immunohistochemistry, molecular biology.

Prof. Yan Zhang received his Ph.D. in Organic Chemistry from the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, in 2013. He subsequently conducted postdoctoral research with Dr. Georgios Skiniotis at the University of Michigan Life Sciences Institute (2013–2017) and the Department of Molecular & Cellular Physiology, Stanford University School of Medicine (2017–2018). In 2018, he joined the Zhejiang University School of Medicine as a tenure-track Professor and Principal Investigator, and was promoted to full Professor in 2022. His group leverages cryo-electron microscopy and computationally guided protein design to dissect receptor activation and signaling, and to pioneer new strategies for modulating GPCR function beyond traditional small-molecule drugs. By developing engineered proteins, nanobodies, and allosteric modulators, his team explores novel avenues to precisely regulate receptor activity. His laboratory has elucidated high-resolution structures of diverse GPCR signaling complexes, uncovering unexpected mechanisms of receptor regulation and pharmacology.

Dr Cassie Hatzipantelis is a postdoctoral research fellow with the University of California, Davis Institute for Psychedelics and Neurotherapeutics. She completed her PhD in Drug Discovery Biology from the Monash Institute of Pharmaceutical Sciences, Monash University. Presently as a Project Lead within the IPN, she leads teams across various projects related to the pharmacology of psychedelic drugs and their role in neurophysiology, neuropsychiatric pathophysiology, and in the treatment of neuropsychiatric disorders. Using integrated approaches spanning molecular biology, analytical pharmacology, neurophysiology and behavioural neuroscience Cassie hopes to understand, develop, and advance novel therapeutic agents for the treatment of neuropsychiatric disorders.

Dangge Wang is a principal investigator at Shanghai Jiao Tong University School of Medicine, Shanghai General Hospital. He obtained his B.S. degree at Fudan University and Ph.D degree at Shanghai Institute of Materia Medica, Chinses Academy of Sciences. He has published more than 28 peer-reviewed papers in journals including Sci Immunol, Natl Sci Rev, Sci Adv, Nat Commun, Adv Mater, Nano Today, ACS Nano, Nano Lett, Adv Funct Mater and so on. He has applied more than 10 patents with 6 authorized. His group focuses on improving immunotherapy efficiency in various types of cancer by smart drug delivery systems. He has made a series of contributions to targeted drug delivery systems including the design, construction and mechanistic study of novel nanosized drug delivery systems with higher efficacy and lower toxicity.