Symposium 8: Harnessing a multidisciplinary approach to lactation pharmacology around the world
Tracks
Track 8
Tuesday, July 14, 2026 |
11:15 AM - 1:15 PM |
Details
Breastfeeding is the most affordable, feasible, acceptable, sustainable and safe feeding option for infant and mother. Breastfeeding women are found in every society around the world, and more than half of these will require some form of medication whilst breastfeeding. For many medications, lactation pharmacology studies have not been performed and decisions on risks and benefits to the mother-infant dyad are made ‘in the dark’. This is unacceptable. In this symposium, we bring to together three leading consortia that use innovative clinical, analytical, pharmacometrics, and real-world evidence approaches to fill critical gaps in evidence. The MPRINT (Maternal Pediatric PRecision in Therapeutics) Hub, the ConcePTION Project (lactation related WP3) and the MILK (Maternal and Infant Lactation pharmacoKinetics) group explore infant exposure to medications through lactation. Efforts aim to support regulatory pathways and decisions, drug labelling, and to inform clinical therapy of lactating patients and their children.
Speaker
Prof Karel Allegaert
KU Leuven
Experience with an European Medicines Agency related qualification advice of a PBPK model to simulate lactation related medicine exposure: a personal reflection
Biography
Karel Allegaert is a paediatrician (1999), neonatologist (2000) and clinical pharmacologist (2003), and is currently appointed at KU Leuven, departments of Development and Regeneration, and Pharmaceutical and Pharmacological Sciences as full professor, with an additional appointment as senior consultant (10%) at Erasmus MC, Rotterdam (Hospital Pharmacy). His research has its focus perinatal and pediatric clinical pharmacology and its co-variates (maturational, non-maturational, pharmacogenetics, disease-related).
In a truly international and interdisciplinary connection and collaboration, this resulted in a rather extended scientific output (650 PubMed papers, H index 55, https://www.webofscience.com/wos/author/record/C-3611-2016), and about 50 textbook chapters. The most relevant science categories are pediatrics, pharmacology and pharmacy, medicine research, microbiology and microbiology, toxicology, and lactation-related drug exposure. Links to retrieve the scientific output, as accessible in the public domain: https://www.researchgate.net/profile/Karel-Allegaert.
The commitment to create societal impact is reflected in advisory tasks within the field of pharmacology and medicine, like membership of the commission on human medicines; council member Royal Academy of Medicine Belgium (since 2015); member trial board, KCE Belgium. He is also member of the HCP-WP and member of the expert screening panel on medical devices, of the European Medicines Agency, and highly involved in different pediatric formularies (kinderformularium, Australasian neonatal formulary, MADAM).
Session chair
Francis Ojara
Gulu University/ Infectious Diseases Institute, Makerere University
Catriona Waitt
University Of Liverpool/ Infectious Diseases Institute Makerere Univer
