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Oral Presentations 52: Clinical Pharmacology Geriatric 3

Tracks
Track 4
Friday, July 17, 2026
9:00 AM - 10:30 AM

Speaker

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Prof Simon Dimmitt
Clinical Professor Of Medicine
University of Western Australia, University of Newcastle

Estimated ED50 based on major outcomes in trials can guide clinical dosage

Abstract

Biography

Simon Dimmitt is an Australian Consultant Physician working in General Medicine, Cardiology and Clinical Pharmacology. He is Clinical Professor of Medicine at the University of Western Australia (where he helped established their Lipid Disorders Clinic and Stroke Unit) and Conjoint Professor (Research), School of Medicine & Public Health at the University of Newcastle, New South Wales. His over 100 publications include 5 postgraduate textbooks.
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Dr John Mach
Research Fellow, Laboratory Manager
Kolling Institute/ USYD/ NSLHD

Plasma proteins associated with adverse geriatric outcomes in older people with polypharmacy

Abstract

Biography

Dr John Mach (BScMed(Hons), PhD) is a Research Fellow and Laboratory Manager who leads the basic science branch of the Laboratory of Ageing and Pharmacology, Kolling Institute, University of Sydney and Royal North Shore Hospital. His research applies basic science techniques to samples from preclinical and clinical studies to understand the mechanisms by which chronic medication exposure, polypharmacy and deprescribing cause beneficial and harmful effects in old age. His research aims to inform optimal medication use and deprescribing for older people.
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Mr Kevin Winardi
Scientific Officer
Kolling Institute, Northern Sydney Local Health District and the University of Sydney

A Systems Pharmacology Approach to Classification of Drugs with Anticholinergic Effects

Abstract

Biography

Kevin Winardi is a scientific officer in the Laboratory of Ageing and Pharmacology led by Prof Sarah Hilmer at the Kolling Institute, operating in partnership with the University of Sydney and the Northern Sydney Local Health District. His work integrates systems biology, pharmacology, and biogerontology to understand drug response and its impact to organ function in the context of ageing. He applies proteomics and systems pharmacology approaches to better delineate the molecular complexity of multiple medication usage (polypharmacy), drug-induced harms, and medication cessation (deprescribing). His long-term goal is to advance precision prescribing and improve medication safety practices for older adults through translational ageing research.
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Dr Tsakani Rasakanya
Senior Lecturer
Sefako Makgatho Health Science University

Effects of oral hypoglycaemics on arterial elasticity, endothelial dysfunction and pro-inflammatory cytokines

Abstract

Biography

Dr Tsakani Locrecia Rasakanya is a Senior Lecturer and Research Coordinator in the Department of Pharmacology and Therapeutics at Sefako Makgatho Health Sciences University, Ga-Rankuwa, South Africa. She earned her PhD in Pharmacology from SMU (2023), an MSc and BSc (Hons) in Pharmacology from the University of Pretoria (2014, 2009), and a BSc in Medical Cell Biology and Human Physiology from the University of the Witwatersrand (2008). Dr Rasakanya holds academic leadership roles as Academic Coordinator for Postgraduate Studies and Research and for the Nursing Programme in her department. She serves on multiple university committees, including the School of Medicine Research and Ethics Committee, the Curriculum Development Committee, and the Postgraduate Examination Committee, and is an Executive Committee member of the South African Society of Basic and Clinical Pharmacology. Her research focuses on clinical pharmacology and cardiovascular health, with interests in inflammatory markers, arterial stiffness, and pharmacological interventions in metabolic diseases. She has authored several peer-reviewed publications and has received numerous awards, including the Young Pharmacologist Award for Best Podium Presentation (2023), Best Publication Award in Clinical Pharmacology (2024), and First Place for Podium Presentation at SMU’s School of Medicine Research Day (2025).
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Dr Yohanes Wondimkun
Adelaide University

DPP-4 safety inhibitors among people with diabetes in residential aged care homes

Abstract

Biography

Dr. Yohanes Wondimkun is a Research Fellow in the School of Allied Health and Human Performance, College of Health, Adelaide University. Yohanes is a pharmacist with a special interest in geriatric pharmacoepidemiology. His research work focuses on improving medication use and health outcomes among older people using real-world data.
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Ms Annie ML Ea
Monash University

Turning evidence-into-action: a process evaluation of guideline implementation strategies in aged care

Abstract

Biography

Annie Ea is a PhD Candidate from the Centre for Medicine Use and Safety at Monash University. Her research investigates the role of knowledge brokers to implement clinical practice guidelines for safe and effective medication management. She is particularly interested in improving guideline implementation in residential aged care. Annie obtained her Bachelor of Pharmacy (Honours) and Master of Pharmacy at Monash University. Alongside her PhD, Annie serves as Lead Pharmacist at St John Ambulance Victoria and continues to practice as a clinical pharmacist in general and geriatric medicine.
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